Roughley, Stephen: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

Roughley, Stephen D., Jordan, Allan M.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.57 MB

english, 2011

2

Oto-palato-digital syndrome, type II: Report of three cases with further delineation of the chondro-osseous morphology

Ravi Savarirayan, Valérie Cormier-Daire, Sheila Unger, Ralph S. Lachman, Peter J. Roughley, Stephen F. Wagner, David L. Rimoin, William R. Wilcox

Journal:

American Journal of Medical Genetics Part A

Year:

2000

Language:

english

File:

PDF, 821 KB

english, 2000

3

ChemInform Abstract: Synthesis of (-)-Histrionicotoxin (I) by a Tandem Process.

Geoffrey M. Williams, Stephen D. Roughley, John E. Davies, Andrew B. Holmes, Joseph P. Adams

Journal:

Year:

1999

File:

PDF, 25 KB

1999

4

Structure-Based Design of Agents Targeting the Bacterial Ribosome.

Justin Bower, Martin Drysdale, Richard Hebdon, Allan Jordan, Georg Lentzen, Natalia Matassova, Alastair Murchie, Jenifer Powles, Stephen Roughley

Journal:

Year:

2003

File:

PDF, 97 KB

2003

5

ChemInform Abstract: The Medicinal Chemist′s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

Stephen D. Roughley, Allan M. Jordan

Journal:

Year:

2011

File:

PDF, 18 KB

2011

6

Fatty acid amide hydrolase inhibitors. 2. Novel synthesis of sterically hindered azabenzhydryl ethers and an improved synthesis of VER-156084

Stephen D. Roughley, Terance Hart

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 800 KB

english, 2010

7

Structure-based design of agents targeting the bacterial ribosome

Justin Bower, Martin Drysdale, Richard Hebdon, Allan Jordan, Georg Lentzen, Natalia Matassova, Alastair Murchie, Jenifer Powles, Stephen Roughley

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 160 KB

english, 2003

8

A comparative evaluation of the small leucine-rich proteoglycans of pathological human intervertebral discs

Sharon Brown, James Melrose, Bruce Caterson, Peter Roughley, Stephen M. Eisenstein, Sally Roberts

Journal:

European Spine Journal

Year:

2012

Language:

english

File:

PDF, 345 KB

english, 2012

9

Fatty acid amide hydrolase inhibitors. 3: Tetra-substituted azetidine ureas with in vivo activity

Stephen D. Roughley, Helen Browne, Alba T. Macias, Karen Benwell, Teresa Brooks, Jalanie D’Alessandro, Zoe Daniels, Sarah Dugdale, Geraint Francis, Ben Gibbons, Terance Hart, Timothy Haymes, Guy Kenne

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

10

Drug discovery chemistry: a primer for the non-specialist

Allan M. Jordan, Stephen D. Roughley

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 688 KB

english, 2009

11

Intramolecular nitrone dipolar cycloadditions: control of regioselectivity and synthesis of naturally-occurring spirocyclic alkaloids

Hodges, Alastair J., Adams, Joseph P., Bond, Andrew D., Holmes, Andrew B., Press, Neil J., Roughley, Stephen D., Ryan, John H., Saubern, Simon, Smith, Catherine J., Turnbull, Michael D., Newton, Annab

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 651 KB

english, 2012

12

Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design

Dymock, Brian W., Barril, Xavier, Brough, Paul A., Cansfield, Julie E., Massey, Andrew, McDonald, Edward, Hubbard, Roderick E., Surgenor, Allan, Roughley, Stephen D., Webb, Paul, Workman, Paul, Wright

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

13

How Well Can Fragments Explore Accessed Chemical Space? A Case Study from Heat Shock Protein 90

Roughley, Stephen D., Hubbard, Roderick E.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 7.08 MB

english, 2011

14

Nitrone dipolar cycloaddition routes to piperidines and indolizidines. Part 9.Part 8. See Ref. 22. Formal synthesis of (–)-pinidine and total synthesis of (–)-histrionicotoxin, (+)-histrionicotoxin and (–)-histrionicotoxin 235AThis manuscript is dedicated to the sixtieth birthday of Professor L. Tietze.

Davison, Edwin C., Fox, Martin E., Holmes, Andrew B., Roughley, Stephen D., Smith, Catherine J., Williams, Geoffrey M., Davies, John E., Raithby, Paul R., Adams, Joseph P., Forbes, Ian T., Press, Neil

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2002

Language:

english

File:

PDF, 426 KB

english, 2002

15

Trimethoprim/sulfamethoxazole (co-trimoxazole) prophylaxis is effective against acute murine inhalational melioidosis and glanders

Barnes, Kay B., Steward, Jackie, Thwaite, Joanne E., Lever, M. Stephen, Davies, Carwyn H., Armstrong, Stuart J., Laws, Thomas R., Roughley, Neil, Harding, Sarah V., Atkins, Timothy P., Simpson, Andrew

Journal:

International Journal of Antimicrobial Agents

Year:

2013

Language:

english

File:

PDF, 417 KB

english, 2013

16

Off-Rate Screening (ORS) By Surface Plasmon Resonance. An Efficient Method to Kinetically Sample Hit to Lead Chemical Space from Unpurified Reaction Products

Murray, James B., Roughley, Stephen D., Matassova, Natalia, Brough, Paul A.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 287 KB

english, 2014

17

Synthesis of (−)-Histrionicotoxin by a Tandem Process

Williams, Geoffrey M., Roughley, Stephen D., Davies, John E., Holmes, Andrew B., Adams, Joseph P.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 78 KB

english, 1999

18

Dynamic undocking and the quasi-bound state as tools for drug discovery

Ruiz-Carmona, Sergio, Schmidtke, Peter, Luque, F. Javier, Baker, Lisa, Matassova, Natalia, Davis, Ben, Roughley, Stephen, Murray, James, Hubbard, Rod, Barril, Xavier

Journal:

Nature Chemistry

Year:

2016

Language:

english

File:

PDF, 5.27 MB

english, 2016

19

Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures

Baker, Lisa M., Aimon, Anthony, Murray, James B., Surgenor, Allan E., Matassova, Natalia, Roughley, Stephen D., Collins, Patrick M., Krojer, Tobias, von Delft, Frank, Hubbard, Roderick E.

Journal:

Communications Chemistry

Year:

2020

File:

PDF, 1.33 MB

2020

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски